Major Sources of Post-column Peak Broadening in nanoLC

[ APPLICATION NOTE ] Evaluating the Impact of LC System Dispersion on the Size-Exclusion Chromatography Analysis of Proteins Stephan M. Koza, Corey E. Reed, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Understanding the measurement Size-exclusion…

TECHNICAL NOTE 74068 Increase sensitivity in UHPLC-MS analysis by minimizing post-column dispersion Authors: Soo Hyun Park, Mauro De Pra, Giorgia Greco Thermo Fisher Scientific, Germering, Germany Keywords: System dispersion, post-column dispersion, UHPLC, pesticides, Vanquish Horizon, ISQ EM, ISQ EC, high-throughput…

TECHNICAL NOTE 72899 Tandem nanoLC-MS: maximum MS utilization for deep-dive proteomic analysis Table of Contents Authors Christopher Pynn , Alexander Boychenko1, Wim Decrop1, Mike Baynham2, Peter Jehle1, Martin Ruehl1 1 Thermo Fisher Scientific, Germering, Germany 1 Thermo Fisher Scientific, Runcorn,…

[ CARE AND USE MANUAL ] XSelect Peptide CSH C18 , 130Å, 3.5 µm and 5 µm Columns CONTENTS I. GETTING STARTED a. Column Installation b. Column Equilibration c. Initial Column Efficiency Determination Thank you for choosing a Waters® XSelect®…