A NEW LC-MS APPROACH FOR SYNTHETIC PEPTIDE CHARACTERIZATION AND IMPURITY PROFILING

[ APPLICATION NOTE ] Synthetic Peptide Characterization and Impurity Profiling Using a Compliance-Ready LC-HRMS Workflow Nilini Ranbaduge and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ A compliance-ready solution for peptide Peptide-based therapeutics are alpha amino…

Application Note Biotherapeutic Peptide Mass Confirmation and Impurity Profiling on a SmartMS Enabled BioAccord LC-MS System Kiran Krishnan, Sumit Bobhate, Raghu Tadala, Dr. Padmakar Wagh Waters Corporation Abstract This application note demonstrates how BioAccord LC-MS System can be used for…

[ APPLICATION NOTE ] LC-UV-MS-based Synthetic Peptide Identification and Impurity Profiling Using the ACQUITY QDa Detector with ProMass Software Ximo Zhang, Brooke Koshel, Jing Fang, William Alley, Robert Birdsall, and Yinq Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS…

[ TECHNOLOGY BRIEF ] An Integrated LC-MS Workflow with ProMass HR for Synthetic Peptide Impurity Analysis Ximo Zhang, William R. Alley, Robert E. Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA High-resolution characterization of synthetic peptide impurities using…