Complementary Dual LC as a convenient alternative to multiple heart-cut 2D-LC for samples of medium complexity

TECHNICAL NOTE 73298 Flexible HPLC instrument setups for double usage as one heart-cut-2D-LC system or two independent 1D-LC systems Authors: Maria Grübner and Giorgia Greco Thermo Fisher Scientific, Germering, Germany Keywords: Two-dimensional liquid chromatography, 2D-LC, 2D-HPLC, heart-cut-2D-LC, Vanquish Duo UHPLC…

CUSTOMER APPLICATION NOTE 74149 Complementary analysis in a biopharmaceutical research laboratory with a 2D-LC-MS instrument for flexible operation Authors: Dr. Valentino Konjik, Ascendis Pharma GmbH, Heidelberg, Germany Maria Grübner, Thermo Fisher Scientific, Germering, Germany Keywords: Biopharmaceutical, therapeutic proteins, 2D-LC, size…

CUSTOMER APPLICATION NOTE 74149 Complementary analysis in a biopharmaceutical research laboratory with a 2D-LC-MS instrument for flexible operation Authors: Dr. Valentino Konjik, Ascendis Pharma GmbH, Heidelberg, Germany Maria Grübner, Thermo Fisher Scientific, Germering, Germany Keywords: Biopharmaceutical, therapeutic proteins, 2D-LC, size…

Complementary Dual LC as Alternative to Multi Heart-Cut LC for Samples of medium Complexity resulting in improved Precision, Sensitivity and Productivity Sylvia Grosse, Maria Grübner, Frank Steiner, Mauro De Pra, Thermo Fisher Scientific, Dornierstrasse 4, 82110 Germering, Germany RESULTS Table…