Complementary analysis in a biopharmaceutical research laboratory with a 2D-LC-MS instrument for flexible operation

CUSTOMER APPLICATION NOTE 74149 Complementary analysis in a biopharmaceutical research laboratory with a 2D-LC-MS instrument for flexible operation Authors: Dr. Valentino Konjik, Ascendis Pharma GmbH, Heidelberg, Germany Maria Grübner, Thermo Fisher Scientific, Germering, Germany Keywords: Biopharmaceutical, therapeutic proteins, 2D-LC, size…

TECHNICAL NOTE 73298 Flexible HPLC instrument setups for double usage as one heart-cut-2D-LC system or two independent 1D-LC systems Authors: Maria Grübner and Giorgia Greco Thermo Fisher Scientific, Germering, Germany Keywords: Two-dimensional liquid chromatography, 2D-LC, 2D-HPLC, heart-cut-2D-LC, Vanquish Duo UHPLC…

TECHNICAL NOTE No. 73184 Complementary Dual LC as a convenient alternative to multiple heart-cut 2D-LC for samples of medium complexity Authors: Maria Grübner, Frank Steiner, Thermo Fisher Scientific, Germering, Germany Keywords: Polyphenols, Dual LC, parallel LC, two-dimensional liquid chromatography, 2D-LC,…

Application note | 003310 Biopharma Monitoring of multiple quality attributes of intact monoclonal antibodies from bioreactors by switchable 2D-LC-MS Authors Application benefits Maria Grübner , Kai Scheffler , 1 1 • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of…