Online 2D-nanoLC hyphenated with high-resolution accurate-mass Orbitrap mass spectrometry for comprehensive and robust proteome profiling

Low-flow On-line 2D LCMS Hyphenated with HRAM MS for Comprehensive Proteome Profiling Oleksandr Boychenko, Christopher Pynn, Wim Decrop, Peter Jehle, Mauro De Pra, Thermo Fisher Scientific, Dornierstr. 4, Germering, Germany, 82205 ABSTRACT Purpose: Develop an automated on-line 2D setup and…

Novel On-Line Multidimensional Low-Flow LCMS Setups for Comprehensive and Fast Proteome Profiling Oleksandr Boychenko; Christopher Pynn; Wim Decrop, Peter Jehle, Sylvia Grosse; Thermo Fisher Scientific, Germering, Germany VWD-3400RS NCS-3500RS The goal to achieve deeper proteome coverage requires longer analysis times…

Comprehensive and Robust Proteome Profiling using Online-2D NanoLC coupled to the Orbitrap Exploris 480 MS Tabiwang N. Arrey1, Runsheng Zheng2, Alexander Boychenko2, Alexander Harder1 1Thermo Fisher Scientific, Bremen, Germany, 2 Thermo Fisher Scientific, Germering, Germany INTRODUCTION RESULTS Although high proteome…

TECHNICAL NOTE 72899 Tandem nanoLC-MS: maximum MS utilization for deep-dive proteomic analysis Table of Contents Authors Christopher Pynn , Alexander Boychenko1, Wim Decrop1, Mike Baynham2, Peter Jehle1, Martin Ruehl1 1 Thermo Fisher Scientific, Germering, Germany 1 Thermo Fisher Scientific, Runcorn,…