Comprehensive and Robust Proteome Profiling using Online-2D NanoLC coupled to the Orbitrap Exploris 480 MS

TECHNICAL NOTE 73291 Online 2D-nanoLC hyphenated with high-resolution accurate-mass Orbitrap mass spectrometry for comprehensive and robust proteome profiling Authors: Runsheng Zheng1, Alexander Boychenko1, Tabiwang N. Arrey2, Christopher Pynn1, Wim Decrop1, Peter Jehle1 Thermo Fisher Scientific, Germering, Germany; 2Thermo Fisher Scientific,…

Novel On-Line Multidimensional Low-Flow LCMS Setups for Comprehensive and Fast Proteome Profiling Oleksandr Boychenko; Christopher Pynn; Wim Decrop, Peter Jehle, Sylvia Grosse; Thermo Fisher Scientific, Germering, Germany VWD-3400RS NCS-3500RS The goal to achieve deeper proteome coverage requires longer analysis times…

Low-flow On-line 2D LCMS Hyphenated with HRAM MS for Comprehensive Proteome Profiling Oleksandr Boychenko, Christopher Pynn, Wim Decrop, Peter Jehle, Mauro De Pra, Thermo Fisher Scientific, Dornierstr. 4, Germering, Germany, 82205 ABSTRACT Purpose: Develop an automated on-line 2D setup and…

Precise Quantitative Serum LC-MS/MS Profiling: The Impact of Sample Preparation and Sample Source on Biomarker Discovery Studies Alexander Boychenko1, Natalia Govorukhina2, Runsheng Zheng1 1Thermo Fisher Scientific, Germering, Germany of Groningen, Groningen, The Netherlands 2University 1 For Research Use Only. Not…