Advancing native top-down MS analysis of non-covalent protein complexes: The Thermo Scientific Q Exactive UHMR mass spectrometer

Advances in Orbitrap Instrumentation for Native Top-Down Analysis of Non-Covalent Protein Complexes Eugen Damoc1, Rosa Viner2, Albert Konijnenberg3, Kyle Fort1, Maria Reinhardt-Szyba1, Mikhail Belov1, Alexander Makarov1. 1Thermo Fisher Scientific, Bremen, Germany; 2Thermo Scientific, San Jose, CA; 3Thermo Fisher Scientific, Eindhoven,…

Go beyond what you thought possible with native MS Thermo Scientific Q Exactive UHMR Hybrid Quadrupole-Orbitrap mass spectrometer Gain deeper insight into native proteins Native mass spectrometry (MS) is a powerful technique for studying the structure of large protein complexes,…

PRODUCT SPECIFICATIONS Q Exactive UHMR Hybrid Quadrupole-Orbitrap mass spectrometer Delivering unmatched identification and characterization Keywords Orbitrap technology, Q Exactive family, accurate mass, high resolution, native ms, ultra-high mass range Benefits • U  ltra-high mass range up to m/z 80,000…

Analytical solutions for biopharmaceutical characterization and control Your partner on every step of your journey Together we can address the challenges of biotherapeutic drug development Your molecules are complex Biotherapeutics such as monoclonal antibodies, biosimilars, antibody-drug conjugates, and nucleotide-based therapies…