Multiplexing SIMs on a Novel Benchtop Orbitrap MS with a Quadrupole Mass Filter to Increase Sensitivity for Peptide Quantitation

Multiple C-Trap or HCD Fills as a Tool for Massive Parallelization of Orbitrap Mass Spectrometry – AN New C Conceptt ffor T Targeted t dM Mass A Analysis l i Oliver Lange, Jan-Peter Hauschild, Alexander Makarov, Ulf Fröhlich, Catharina Crone,…

A Complete Workflow Solution for Intact Monoclonal Antibody Characterization Using a New High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS Zhiqi Hao,1 Yi Zhang,1 David Horn,1 Seema Sharma,1 Shiaw-Lin Wu, 2 Irene Ae-Ning Lin, 3 Yi-Hsuan Pan, 3 Ya-Fen Yang, 3 and Andreas F.…

Mindy Gao, Joe Di Bussolo, Marta Kozak Thermo Fisher Scientific, San Jose, CA Key Words Q Exactive Focus, methylmalonic acid, MMA, clinical research Goal To evaluate the performance of the Thermo Scientific™ Q Exactive™ Focus benchtop quadrupole-Orbitrap mass spectrometer as…

Methods Calibrators Calibrators containing cyclosporin A, everolimus, sirolimus, and tacrolimus in whole blood were purchased from Chromsystems Instruments & Chemicals GmbH (TABLE 1). Evaluation of Benchtop Quadrupole Orbitrap Ultra-High-Resolution Mass Spectrometer in Rapid Quantitative Analysis of Immunosuppressant Evaluation of Benchtop…