Same Day HCP Workflow Has Become Reality!

Standardized, high-throughput platform for automated, rapid, and extensive plasma proteome characterization Claudia Martelli1*; Fabian Wendt2*+; Andreas Schmidt3; Katrin Hartinger4; Gary Kruppa5; Nils A. Kulak4; Manuel Bauer2 1Bruker Switzerland AG, Fällanden, Switzerland; 2Tecan, Männedorf, Switzerland; 3Bruker Daltonics GmbH & Co. KG,…

In Depth Analysis of Host Cell Proteins from Antibody Preparations using PASEF Introduction In the rapidly expanding arena of biotherapeutic analysis and bioprocess development, the analysis of host cell proteins (HCPs) at the ppm level is critical. ELISA is currently…

Biopharma Whitepaper Advanced host cell protein (HCP) analysis with TIMS QTOF MS powers biopharmaceutical development Introduction The recent rapid expansion of the biopharmaceutical field is driving the growth of biotherapeutic analysis and bioprocess development. The percentage of large molecules in…

ASMS 2025 – WP660 Optimizing LC-MS/MS settings for plasma proteomics analysis with cap-flow LC separation and dia-PASEF Chromatographic gradients were optimized for direct injection, short separation with consistent peak width and minimal carry-over and equilibration time. (fig. 1 B) ▪…