Accurate Label-Free Protein Quantitation on the timsTOF Pro with 4D-Proteomics™

diaPASEF: label-free quantification of highly complex proteomes The timsTOF Pro with diaPASEF provides reproducible and accurate qualitative and quantitative results in complex proteomics samples – making it perfectly suited for data-independent acquisition approaches. Abstract Data-independent acquisition (DIA) promises reproducible and…

High throughput 4D-Proteomics – Application of dia-PASEF® and the Evosep One for short gradients The timsTOF Pro offers a combination of two unique technologies, namely a 4th dimension provided by Trapped Ion Mobility Spectrometry (TIMS) to enhance ion separation and…

Short gradients with Bruker’s nanoElute coupled to the timsTOF Pro with PASEF —Throughput and deep proteome measurements The nanoElute optimized for high throughput in chromatographic separation together with the timsTOF Pro powered by PASEF and the additional dimension of separation…

PASEF™ on a timsTOF Pro defines new performance standards for shotgun proteomics with dramatic improvements in MS/MS data acquisition rates and sensitivity Trapped ion mobility spectrometry coupled with quadrupole time-of-flight mass spectrometry (timsTOF Pro) offers a unique dimension of characterization…