Incorporating CCS values to enable 4-dimensional annotation of metabolic features

Investigating the increased lifespan in C. elegans daf-2 mutants by 4D-Lipidomics The small nematode Caenorhabditis elegans is one of the premier biomedical model organisms and employed in many aspects of basic and applied science Introduction Typical application areas for C.…

Intensity (arb. unit) 132% 0% 100% PS 38:1 m/z 816.5747 ± 0.0122 1/K0 1.433 ± 0.01 Intensity (arb. unit) Mobility [1/K0] 136% 0% 100% PE 20:1_22:6 m/z 816.5517 ± 0.0122 1/K0 1.404 ± 0.01 m/z 1 mm CCS-aware SpatialOMx® enables…

4D-Lipidomics™ workflow for increased throughput Lipid profiling from complex lipid extracts can be a challenging and time consuming task. The high complexity of samples and co-elution of isobaric or isomeric compounds complicate the confident annotation of lipids. The presented 4D-Lipidomics…

ASMS 2023, THP 385 Profiling and quantitation of bile acids in human biofluids by LC-TIMS-MS Results Aiko Barsch1; Surendar Tadi², Xuejun Peng³, Narayanaganesh Balasubramanian², Elena Checkmeneva4, Katie E. Chappell4, Niels Goedecke1, Matthew R. Lewis1 1Bruker Daltonics GmbH & Co. KG,…