Automating Metabolic Stability Assays and Analyses using a Robotic Autosampler and LC/MS/MS Platform

Application Note Drug Discovery Ultrafast Analysis of Metabolic Stability Assays Using Agilent RapidFire High-Resolution MS Authors Michelle V. Romm, Nikunj Parikh, and Vaughn P. Miller Agilent Technologies, Inc. Wakefield, MA Yuqin Dai Agilent Technologies, Inc. Santa Clara, CA Abstract The…

Application Note Drug Discovery Ultrafast Analysis of Metabolic Stability Assays using an Agilent Ultivo Triple Quadrupole LC/MS Author Kevin McCann Agilent Technologies, Inc. Abstract A previous Application Note1 highlighted the advantages of using the Agilent RapidFire 365 high-throughput MS to…

Application Note Analytical Solutions for High Throughput ADME Studies Marian Twohig, Robert S. Plumb, Amy Bartlett, Peter Hancock Waters Corporation Abstract High throughput ADME (absorption, distribution, metabolism, and elimination) plays a critical role in identifying viable drug candidates in the…

GERSTEL Application Note No. 215, 2020 Automated Hydrolysis, Extraction and Analysis of Synthetic Cathinones in Urine using a Robotic Autosampler and LC-MS/MS Platform Fred D. Foster1 and John R. Stuff1 1. GERSTEL, Inc., 701 Digital Drive, Suite J, Linthicum, MD…