Analytical Solutions for High Throughput ADME Studies

Rapid Detection and Quantification of Selected Microsomal Substrates and Metabolites Using the Waters ACQUITY UPLC I-Class System and Xevo TQ-S micro Kerri M. Smith and Paul D. Rainville Waters Corporation, Milford, MA, USA A P P L I C AT…

AUTOMATED LC/MS/MS HIGH THROUGHPUT MULTI-MODE IONIZATION QUANTIFICATION PROTOCOL APPLIED FOR MICROSOME STABILITY TEST IN DRUG DISCOVERY AND DEVELOPMENT Waters Kate Yu1, Darcy Shave1, Peter Alden1, Rob Plumb1, Li Di2, Susan Li2, Edward Kerns2, Paul Chilvers3 1. Waters Corporation, Milford, MA;…

Application Note Drug Discovery Ultrafast Analysis of Metabolic Stability Assays Using Agilent RapidFire High-Resolution MS Authors Michelle V. Romm, Nikunj Parikh, and Vaughn P. Miller Agilent Technologies, Inc. Wakefield, MA Yuqin Dai Agilent Technologies, Inc. Santa Clara, CA Abstract The…

A P P LICAT ION SOLUT IONS FO R M ETABOLIT E IDENT IFICAT ION A P P L I C AT I O N S O L U T I O N S F O R M E TA…