Large-Scale Lipid Profiling of a Human Serum Lipidome Using a High-Resolution, Accurate-Mass LC/MS/MS Approach

Robust and Sensitive LC-MS/MS Based Plasma Lipid Profiling on a Thermo Scientific Q Exactive HF-X Mass Spectrometer Tabiwang N. Arrey1, Elena Sokol2, Angela Criscuolo1, Claire Dauly3, Alexander Harder1, Thermo Fisher Scientific, 1Bremen, Germany, 2Hemel Hempstead, UK, 3Villebon-sur-Yvette, France Plasma Extraction…

Results: Fatty acids comprising the molecular phospholipid species were unambiguously identified. ne Proteome Discoverer software is a node-based workflow engine and study management 55 platform for analysis of mass spectrometry-based proteomics datasets. The latest released version 2.1 fully supports isotopically-labeled…

Higher Resolution LC-MS and MS-MS Analysis of Lipid Extracts Using Benchtop Orbitrap-based Mass Spectrometers and LipidSearch Software David A Peake,1 Yasuto Yokoi, 2 Reiko Kiyonami1 and Yingying Huang1 1 Thermo Fisher Scientific, San Jose, USA; 2Mitsui Knowledge Industry, Tokyo, JAPAN…

Li three lean and three fatty Zucker rats were analyzed. With the multiple “omics” workflows developed here we were able to simultaneously identify quantify hundreds of individualto unbiased clinical biomarker discovery research of Application of and “omics” technologies molecular lipid…