Charge Variant analysis of mAb Biosimilars by Nexera UHPLC with a Shim-pack Bio IEX Column

Liquid Chromatograph NexeraTM XS Application News Charge variant analysis of mAb biotherapeutics by Nexera XS with a Shim-pack Bio IEX Column Ashutosh Shelar1 , Bhaumik Trivedi 1 , Navin Devadiga1, and Krutika Padhye 2 1 Shimadzu Analytical (India) Pvt. Ltd.,…

Application News No. AD-0227 Biopharma / Nexera Bio UHPLC / Shim-pack Bio IEX Exploring Factors That Influence Charge Variant Analysis of mAbs with Shim-packTM Bio IEX Columns using Salt Gradient Elution ❑ Introduction Protein-based therapeutic drugs including monoclonal antibodies (mAbs)…

Charge Heterogeneity Analysis of Rituximab Innovator and Biosimilar mAbs Application Note Author Abstract Suresh Babu C.V. This Application Note describes the high-resolution separation of charge variants Agilent Technologies India Pvt. Ltd, of innovator and biosimilar rituximab using an Agilent 1260…

Application Note Pharma & Biopharma Charge Variant and Aggregation Analysis of Innovator and Biosimilars of Rituximab Author Bian Yulan Global Solution Development Center, Global Laboratory Solution Sales (LSS) Marketing, Agilent Technologies Singapore (Sales) Pte. Ltd. Abstract Monoclonal antibodies are an…