Charge Variant and Aggregation Analysis of Innovator and Biosimilars of Rituximab

Charge Heterogeneity Analysis of Rituximab Innovator and Biosimilar mAbs Application Note Author Abstract Suresh Babu C.V. This Application Note describes the high-resolution separation of charge variants Agilent Technologies India Pvt. Ltd, of innovator and biosimilar rituximab using an Agilent 1260…

Seamless Method Transfer from an Agilent 1260 Infinity Bio-inert LC to an Agilent 1260 Infinity II Bio-inert LC Charge Variant Analysis of Rituximab Innovator and Biosimilar Application Note Biologics & Biosimilars Author Abstract Sonja Schneider Monitoring the charge heterogeneity of…

Analysis of Charge Heterogeneity in Rituximab Innovator and Biosimilar Monoclonal Antibodies Using Salt-Gradient Cation Exchange Chromatography Suresh Babu C.V., Salman Lateef Syed, Siji Joseph Agilent Technologies India Pvt. Ltd., Bangalore, India HPLC 2015 PSA-BIO-08 Introduction Results and Discussion Agilent Buffer…

Separate and Quantify Rituximab Aggregates and Fragments with High-Resolution SEC The Agilent 1260 Infinity Bio-Inert Quaternary LC System and the AdvanceBio SEC 300Å, 2.7 µm Column Application Note Biologics and Biosimilars Author Abstract M.Sundaram Palaniswamy Monoclonal antibody aggregation can arise…