Charge Heterogeneity Analysis of Rituximab Innovator and Biosimilar mAbs

Analysis of Charge Heterogeneity in Rituximab Innovator and Biosimilar Monoclonal Antibodies Using Salt-Gradient Cation Exchange Chromatography Suresh Babu C.V., Salman Lateef Syed, Siji Joseph Agilent Technologies India Pvt. Ltd., Bangalore, India HPLC 2015 PSA-BIO-08 Introduction Results and Discussion Agilent Buffer…

Agilent Biocolumns Charge Variant Analysis Application Compendium Contents Background 2 Getting Started 3 How to Guide - Ion-Exchange Chromatography for Biomolecule Analysis - 5991-3775EN 4 Featured Application Notes 22 Convenient Customization of Your Cation Exchange Analysis 5994-3257EN  22 How…

Monoclonal Antibody Charge Heterogeneity Analysis by CZE and CZE/MS Comparison of charge variant profiles of Rituximab Innovator and Biosimilar mAbs Application Note Biopharmaceutical Author Introduction Suresh Babu C.V. During biosysnthesis, various post-translational modifications (PTMs) will lead to charge heterogeneity in…

Application Note Pharma & Biopharma Charge Variant and Aggregation Analysis of Innovator and Biosimilars of Rituximab Author Bian Yulan Global Solution Development Center, Global Laboratory Solution Sales (LSS) Marketing, Agilent Technologies Singapore (Sales) Pte. Ltd. Abstract Monoclonal antibodies are an…