High Spatial Resolution Molecular Tissue Imaging by Desorption Electrospray Ionization (DESI) using Novel Sprayer Assembly

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

Multiple, Sequential DESI Images from a Single Tissue Section at Different Spatial Resolution Emmanuelle Claude and Emrys Jones Waters Corporation, Wilmslow, UK G OA L DESI imaging allows multiple analyses of a single To demonstrate that desorption electrospray ionization (DESI)…

TARGETED DESI IMAGING MS OF DRUG DISTRIBUTION AND DRUGINDUCED LIVER INJURY (DILI) METABOLITES FROM METHAPYRILENE IN THE MALE WISTAR RAT Anthony Midey,1 Emmanuelle Claude,2 Lisa Reid,2 Bindesh Shrestha,1 Steven K Lai,1 Ian D Wilson,3 Robert S Plumb,1 and Roy Martin1…

Utility of Desorption Electrospray Ionization (DESI) for Mass Spectrometry Imaging Emmanuelle Claude and Emrys Jones G OA L DESI imaging provides effective and meaningful To describe the DESI imaging technique as applied to mass spectrometry imaging using time-of-flight (TOF) mass…