Utility of Desorption Electrospray Ionization (DESI) for Mass Spectrometry Imaging

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

[ TECHNOLOGY BRIEF ] Metabolic Phenotyping of Colorectal Tissue Samples by DESI-MSI for Clinical Research Anna Mroz,¹ Luisa Doria,¹ Emmanuelle Claude,² and Zoltan Takats¹ ¹Imperial College, London, UK; ²Waters Corporation, Wilmslow, UK The examination of lipid profiles and distributions in…

[ TECHNOLOGY BRIEF ] Application of Desorption Electrospray Ionization (DESI) for Breast Tissue Imaging in Clinical Research Dipa Gurung, Imperial College, London, UK; Emmanuelle Claude, Waters Corporation, Wilmslow, UK; and Zoltan Takats, Imperial College, London, UK; DESI imaging provides effective…

Multiple, Sequential DESI Images from a Single Tissue Section at Different Spatial Resolution Emmanuelle Claude and Emrys Jones Waters Corporation, Wilmslow, UK G OA L DESI imaging allows multiple analyses of a single To demonstrate that desorption electrospray ionization (DESI)…