High-Throughput Native HRMS ProA-MS Analysis of mAb Variants in Cell-Culture Samples

Application Note Extended Gradients with Efficient Protein A Columns for the ProA-MS Analysis of mAb and msAb Variants Stephan M. Koza, Chen Gao, Matthew A. Lauber, Stephen J. Shiner Waters Corporation, United States Published on October 23, 2025 Abstract Here,…

High Efficiency Protein A Affinity Columns for the LC-MS and 2D LC-MS Analysis of mAb and msAb A quiver of LC-MS based approaches for the sub-unit and intact and analysis of intact monoclonal antibodies (mAb) and multispecific antibodies (msAb) directly…

Application Note A Trap & Elute Style 2D Protein A–SEC Heart-Cut Method for the Analysis of Monoclonal Antibody Titer and Size Variants in Cell Culture Stephan M. Koza, Steve Shiner, Matthew A. Lauber Waters Corporation, United States Published on June…

Application Note An Easy-to-Execute Direct-Connect 2D Protein A–SEC Method for the Analysis of Monoclonal Antibody Titer and Size Variants in Cell Culture Stephan M. Koza, Beatrice Muriithi, Steve Shiner, and Matthew A. Lauber Waters Corporation, United States Published on May…