High Efficiency Protein A Affinity Columns for the LC-MS and 2D LC-MS Analysis of mAb and msAb

Application Note High-Throughput Native HRMS ProA-MS Analysis of mAb Variants in Cell-Culture Samples Stephan M. Koza, Matthew A. Lauber, Stephen J. Shiner Waters Corporation, United States Published on January 21, 2025 Abstract The use of rapid Protein-A (ProA) 1-minute elution…

Application Note Extended Gradients with Efficient Protein A Columns for the ProA-MS Analysis of mAb and msAb Variants Stephan M. Koza, Chen Gao, Matthew A. Lauber, Stephen J. Shiner Waters Corporation, United States Published on October 23, 2025 Abstract Here,…

Application note | 003310 Biopharma Monitoring of multiple quality attributes of intact monoclonal antibodies from bioreactors by switchable 2D-LC-MS Authors Application benefits Maria Grübner , Kai Scheffler , 1 1 • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of…

A novel approach for multiple PQAs monitoring of mAbs from bioreactors using 2D-LC-MS Maria Grübner a, Christof Mitterer b, Alexander Schwahn c, Aleš Holfeld c, Sara Carillo e, Ken Cook d, Jonathan Bones e a-d Thermo Fisher Scientific (a Germering/Germany;…