Assessment of Biosimilarity in mAb-based Therapeutics Using SEC-MALS

I TEE PPAAPPEERR WWHHI T WP1615: SEC-MALS for absolute biophysical characterization Daniel Some, Ph.D., Waters | Wyatt Technology Summary Accurate characterization of biomacromolecules is essential for successful programs of research and development in the life sciences and biopharmaceuticals. The basic…

WP1621: Multi-Attribute Quantitation of Antibody-Drug Conjugates by LC-MALS Hongjiang (Leo) Liu, Ph.D., and Sophia Kenrick, Ph.D., Wyatt Technology, LLC Summary Liquid chromatography combined with multi-angle light scattering (LC-MALS) is a powerful tool for analyzing antibody-drug conjugates (ADCs), providing a robust…

W H I T E PA P E R WP1618: Enhanced SEC-MALS analysis of therapeutic mAbs, biosimilars and AAVs with XBridge Premier columns Leo Liu, Ph.D., Waters | Wyatt Technology Summary SEC-MALS is widely used for the characterization of biopharmaceuticals.…

PUBLICATION HIGHLIGHTS PH1001: The Role of Multi-Angle Light Scattering in Biosimilar Characterization and Approval Udayabagya Halim, Ph.D, Wyatt Technology, LLC Introduction Bringing a biotherapeutic from the laboratory to the market is a complex and highly regulated process. The approval pathway…