Advancing Chromatographic Performance in Peptide Mapping

A Comprehensive Software Ecosystem for End-to-End Monoclonal Antibody and Antibody–Drug Conjugate Data Acquisition, Analysis, and Reporting Introduction Large and complex biomolecules, such as monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs), constitute a critical class of biopharmaceuticals with diverse therapeutic applications.…

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Poster Reprint ASMS 2026 MP-288 Automated LC/MS System Readiness Assessment for MAM Using Purpose Designed Peptide Standards Mahsan Miladi1, Mike Knierman1, Melissa Sato1, Tristan Chutka1, Andrew McEachran1 1Agilent Technologies Inc., Santa Clara Introduction Experimental Multi-Attribute Method (MAM) workflows require consistent…

Application Note Pharma & Biopharma Fully Automated Characterization of Monoclonal Antibody Charge Variants Using 4D-LC/MS D CEX (DAD) 1 Online 2 D Desalting/Reduction 3 D Digestion 4 D Peptide mapping (MS) Authors Liesa Verscheure, Gerd Vanhoenacker, Pat Sandra, and Koen…