Improving Sensitivity of GLP-1 Analogues Quantitation Using Multiple Spray ESI Technology on a Microflow LC-MS/MS

Supercritical Fluid Chromatography MS/MS Method Development for the Analysis of GLP-1 Analogues MP557 Jonathan Ferguson1; Kathleen Luo1; Brian Domanski1; Risa Suzuki1 1Shimadzu Scientific Instruments, Columbia, MD, USA 1. Introduction Supercritical Fluid Chromatography (SFC), originally developed in the 1960s, had faced…

Agilent biopharma solutions Workflows for GLP-1 Receptor Agonists and Therapeutic Peptides: Identity, Impurity, Bioanalysis, and Stability Testing Contents Raw Material Purity and Impurity Identification Analysis Bioanalysis Stability Testing Studies Contents Introduction 02 1 Raw Material Identification 03 1.1 Verification…

COMPREHENSIVE WORKFLOW FOR QUANTITATIVE BIOANALYSIS OF LARGE PEPTIDES AND PROTEINS: A CASE STUDY OF THE GLP-1 RECEPTOR AGONIST, SEMAGLUTIDE, IN PLASMA Authors: Samantha Ferries1, Suraj Dhungana1, Robert S Plumb2Amy Bartlett 1 Affiliations: 1 WatersTM Corporation, Wilmslow, UK, 2 Waters Corporation,…

Application note | 004408 Pharma Advancing anti-obesity drug development with robust quantitation of GLP-1 analogs using human plasma Authors Application benefits Hao Yang , Neloni Wijeratne , Ke Ma , 1 1 2 • Sensitive and reproducible quantitation of semaglutide…