Comprehensive Workflow for Quantitative Bioanalysis of Large Peptides and Proteins: A Case Study of the GLP-1 Receptor Agonist, Semaglutide, in Plasma

Application Note Comprehensive Workflow for the Quantification of Peptides and Proteins in Plasma: Semaglutide a Case Study Samantha Ferries Waters Corporation Abstract Over the last two decades we have seen a significant increase in protein and peptide-based therapeutics, with “biologics”…

Application Note Comprehensive Workflow for the Quantification of Peptides and Proteins in Plasma: Semaglutide– a Case Study Samantha Ferries Waters Corporation, United States Published on November 11, 2025 Abstract Over the last two decades, there has been a significant increase…

[ APPLICATION NOTEBOOK ] Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape Small Molecules Oligonucleotide Protein/Peptide Therapeutics Software Tools Targeted Imaging LC-MS/MS Solutions to Support Reliable, Sensitive and Efficient Workflows for the Bioanalysis of Drug Modalities Welcome to the Waters…

Application Note Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Measuring Dulaglutide in a Rat PK Study Caitlin Dunning, Mark Wrona Waters Corporation Abstract Development of fusion protein therapeutics, such as dulaglutide (TRULICITYTM), is rising…