Development of a Modified, Compact Single Quadrupole Mass Spectrometer for Quality Control of Oligonucleotides

MP 534 Practical LC–MS Workflows for siRNA and sgRNA Characterization Using a Single-Quadrupole Mass Spectrometer Vikki Johnson1, Kathleen Luo1, Risa Suzuki1,2, Atsuhiko Toyama1,2, Jeff Dahl1, Kosuke Uchiyama2, Toshiya Matsubara1 (1) Shimadzu Scientific Instruments, Columbia, MD. (2) Shimadzu Corporation, Kyoto, Japan.…

A Software Workflow Using Wide Mass Range Single Quadrupole Mass Spectrometry Data Stream Applied to Oligonucleotides Confirmation Risa Suzuki1, 2, Kosuke Uchiyama2, Noriko Kato2, Yuka Fujito2, Jeffery Dahl1, Simon Ashton3, Neil Loftus3, Atsuhiko Toyama2, 4 1Shimadzu Scientific Instruments, Inc., Columbia,…

Liquid Chromatograph Mass Spectrometer LCMS-9030 Q-TOF Understand the rationale behind the Q-TOF LC/MS that stably sustains sub-ppm mass accuracy. Atsuhiko (Ash) Toyama, Ph.D. MS Application Specialist, Analytical & Measuring Instruments Division, Shimadzu Corporation. LCMS-9030 is at its Take Off 2…

High Performance Liquid Chromatograph Mass Spectrometer LCMS™-2050 Application News Using a Single Quadrupole Mass Spectrometer to Check Peptide Synthesis and Analyze Impurities Miho Kawashima and Tomoko Kuriki User Benefits  A single quadrupole mass spectrometer can be used in combination…