A Quality Management System Dashboard for Bruker’s new GlycoTyperTargeted High-Throughput Glycoproteomics Platform

ASMS 2025, TP 082 GlycoTyper - a novel liquid-biopsy platform for high-throughput, high-sensitivity targeted glycoproteomics, exemplified by differentiating Systemic Lupus Erythematosus and Lupus Nephritis Gray Huffman1, Grace Grimsley1, Aaron Angerstein2, Tamara Nowling3, Richard Drake2, Steve Castellino1, and Klaus Lindpaintner1 1Glycobiology…

High-speed MALDI-TOF/TOF imaging of mouse brain tissue performed on intact proteins and after on-tissue digestion The unique flexibility of MALDI-TOF/TOF systems facilitates tissue imaging of intact proteins as well as of tryptic peptides resulting from on-tissue digestion. While intact protein…

MALDI FTMS Imaging Mass Spectrometry of N-glycans as Tissue Biomarkers of Cancer In this application note, we describe preparation and imaging analysis of N-glycans from formalin-fixed paraffin embedded (FFPE) tissues using the solariX MALDI FTMS. N-glycosylation is a common post…

25 YEARS MALDI High-performance MALDI imaging analysis of on-tissue digested proteins in mammalian FFPE tissues using the Bruker rapifleX MALDI-TOF/TOF In this application note, we describe a workflow for MALDI Mass Spectrometry Imaging (MSI) of proteins from a variety of…