Rapid Analysis of Acylcarnitinesin Dried Blood Spots Using Fast Chromatography with Ion Mobility High Resolution Mass Spectrometry

TECHNICAL NOTE 73398 Simultaneous analysis of amino acids, acylcarnitines, and succinylacetone in dried blood spots for research using nonderivatized and derivatized methods Authors: Xiaolei Xie and Marta Kozak Thermo Fisher Scientific, San Jose, CA Keywords: Amino acids, acylcarnitines, succinylacetone, dried…

Xiaolei Xie and Marta Kozak, Thermo Fisher Scientific, San Jose, CA Key Words Amino acids, acylcarnitines, succinylacetone, dried blood spot, nonderivatized, derivatized, TSQ Endura Goal To develop flow injection analysis-tandem mass spectrometry (FIA-MS/MS) research methods for simultaneous detection and quantification…

COLLISION CROSS SECTION ENABLED DESI ION MOBILITY MASS SPECTROMETRY IMAGING Anthony J. Midey, Hernando J. Olivos, and Bindesh Shrestha Waters Corp., Beverly, MA INTRODUCTION Mass spectrometry imaging (MSI) determines the localization of compounds on samples, including tissue sections and drug…

[ APPLICATION NOTEBOOK ] STRUCTURAL ELUCIDATION 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Traditional Herbal Medicine Structural Elucidation using SYNAPT HDMS with Time-Aligned Parallel…