Application Note 205 Determination of Cefepime and Cefepime- Related Substances Using HPLC with UV Detection

Application Note 259 Determination of N-Methylpyrrolidine in Cefepime with Nonsuppressed Conductivity Detection INTRODUCTION Cefepime (Figure 1A) is a semi-synthetic, fourthgeneration cephalosporin with low toxicity and a broad antimicrobial activity range against Gram-negative and Gram-positive bacteria.1, 2 However, this antibiotic is…

Application Note 199 Determination of N-Methylpyrrolidine in Cefepime Using a Reagent-Free Ion Chromatography System Introduction Cephalosporins are currently the most prescribed class of antibiotics worldwide for the treatment of bacterial infections.1 Their low toxicity and broad range antimicrobial activity against…

Acclaim columns overview Columns for challenging separation needs Broad range of HPLC and UHPLC columns Phenyl-1 C30 Mixed-Mode WAX-1 Mixed-Mode WCX-1 Organic acid Surfactant Plus AmG C18 Explosives E2 M Mixed-Mode HILIC-1 ix ed -m Trinity P1 od e Carbamate…

Application Note 195 Determination of Verapamil Hydrochloride Purity Using the Acclaim PA Column INTRODUCTION EQUIPMENT Verapamil-based medications are prescribed for several heart and blood pressure indications. The fastacting formulations (verapamil hydrochloride and Isoptin®) are taken for angina, as well as…