A Faster Solution with Increased Resolution for Determining Chromatographic Identity and Absence of OSCS in Heparin Sodium

Application Note 235 Determination of Oversulfated Chondroitin Sulfate and Dermatan Sulfate in Heparin Sodium Using Anion-Exchange Chromatography with UV Detection INTRODUCTION Heparin, a complex sulfated glycosaminoglycan, is a well-known anticoagulant used to stop or prevent blood from clotting in certain…

Deanna Hurum and Jeffrey Rohrer Thermo Fisher Scientific, Sunnyvale, CA, USA Key Words AminoTrap, Chondroitin Sulfates, Electrochemical Detection , Eluent Generation, RFIC-EG, USP Introduction In early 2008, unusual reactions to heparin, including hypotension, swelling of the larynx, and in some…

Application Note 233 Determination of Galactosamine Containing Organic Impurities in Heparin by HPAE-PAD Using the CarboPac PA20 Column INTRODUCTION In early 2008, unusual reactions to heparin, including hypotension, swelling of the larynx, and in some cases death, prompted a recall…

Thermo Scientific Dionex IonPac IC column selection guide Find the best IC column for your application Thermo Scientific™ Dionex™ IonPac™ Anion Hydroxide Columns Column Part Number - Format (Capacity µeq/col) Recommendations Target Applications Dionex IonPac AS32-Fast-4µm 303151 - 4 x…