Integrated mass spectrometry-based analysis of plasma glycoproteins and their glycan modifications

ASMS, TP381 Integrated MALDI-MSI and Glycopeptide LC-MS/MS Reveal Site- and Region-Specific Glycosylation Changes in Tumor Tissue Results Hongxia Bai1 , Grace Grimsle1, Richard Drake2, Klaus Lindpaintner1 Normal 1Bruker-Daltonics, Life-Science Mass Spectrometry, Billerica, MA, USA; 2 normal Department of Pharmacology, Medical…

LAAN-A-TM-E070 Application News No. B100 MALDI Mass Spectrometer Analysis of Glycopeptides Using MALDImini™-1 Compact MALDI Digital Ion Trap Mass Spectrometer Glycans, which are one post-translational modification of proteins, are molecules with high structural heterogeneity which are formed by complex bonding…

Li three lean and three fatty Zucker rats were analyzed. With the multiple “omics” workflows developed here we were able to simultaneously identify quantify hundreds of individualto unbiased clinical biomarker discovery research of Application of and “omics” technologies molecular lipid…

How to Determine Glycan Profiles of Biopharmaceuticals from Peptide Mapping Data A new and sensitive approach combining BioPharma Compass, PASEF and VIP-HESI Abstract Glycosylation is a common critical quality attribute (CQA) of therapeutic proteins and needs to be characterized during…