MAbPac HIC-Butyl Column High resolution HIC column for monoclonal antibody analysis

Thermo Scientific MAbPac HIC Columns Novel Hydrophobic Interaction HPLC Columns Designed for Monoclonal Antibody Analysis Introduction The Thermo Scientific™ MAbPac™ HIC column family is designed for separations of monoclonal antibodies (mAbs) and related biologics by hydrophobic interaction chromatography (HIC). Their…

150 Absorbance (mAU) including intact mAbs, mAb fragments, engineered variants, and antibody-drug conjugates (ADCs) are being developed for the treatment of cancer and other diseases due to their excellent biocompatibility and high selectivity. The proliferation of monoclonal antibody therapeutics and…

See your protein therapeutics in high resolution Bio LC Columns Contents 2 Introduction to monoclonal antibody (mAb) characterization 3 Affinity titer determination 4 Aggregate separation 5 Charge variant analysis 6 Oxidation variant analysis 11 Antibody drug conjugates (ADCs) analysis 12…

Julia Baek and Xiaodong Liu, Thermo Fisher Scientific, Sunnyvale, CA, USA Appli cat i on N ote 2 1 0 7 9 High-Resolution Separation of Cysteine-Linked Antibody-Drug Conjugate Mimics Using Hydrophobic Interaction Chromatography Key Words Hydrophobic interaction chromatography, HIC, monoclonal…