Development and implementation of a comprehensive fecal metabolites LC-MS library for dietary intervention studies using the Thermo Scientific Stellar mass spectrometer

Metabolomics High throughput targeted metabolomics library generation on a novel mass spectrometer applied to microbiome analysis Bashar Amer1, Cristina Jacob1, Rahul Ravi Deshpande1, Reza Jafari2, Thomas Moehring3, and Susan S. Bird1 1Thermo Fisher Scientific, San Jose, California, United States, 2MetaSci,…

Metabolomics via SQUAD Simultaneous quantitation and discovery (SQUAD) metabolomics workflow on the orbitrap IQ-X for the analysis of fecal bile acids Allison Stewart1, Bashar Amer2, Rahul Deshpande1, Andrew Percy3, Krista Backiel3, Joshua P. Kline2, Brandon Bills2, and Susan Bird2 1ThermoFisher…

SQUAD Analysis Simultaneous quantitation and discovery (SQUAD): an intelligent combination of targeted and untargeted metabolomics workflow for the analysis of fecal metabolites using Orbitrap Astral MS Bashar Amer1, Marie-Pierre Pavageau2, Silvana Biraghi3, Rahul Ravi Deshpande1, Thomas Moehring1, and Susan S.…

Sensitive and selective quantitation of bile acids using targeted MS2/MS3 on the Stellar mass spectrometer Kerry Hassell1, Lauren Bishop1, Jingshu Guo1, Bashar Amer1, Alexey V. Melnik2, James B. Adams3, Rosa Krajmalnik-Brown3, Khemlal Nirmalkar3, Brittany Lee1, Charles E. Maxey1, Cristina C.…