Accurate Collision Cross Sections From Traveling Wave Ion Mobility Measurements in Native Mass Spectrometry – A Structural Investigation of Cas9 Ribonucleoprotein Complexes

Application Note Native Mass Spectrometry of Membrane Protein-Ligand Complexes Using the SELECT SERIES™ Cyclic™ IMS Dale Cooper-Shepherd, Feng Qu, Kleitos Sokratous, Jonathan T. S. Hopper Waters Corporation, OMass Therapeutics This is an Application Brief and does not contain a detailed…

AN IMPROVED CALIBRATION APPROACH FOR TRAVELLING WAVE ION MOBILITY SPECTROMETRY: ROBUST, HIGH-PRECISION COLLISION CROSS SECTIONS Keith Richardson1, David Langridge1, Kevin Giles1, Sugyan Dixit2, Jakub Ujma1, Brandon Ruotolo2 1 Waters Corporation, Altrincham Road, Wilmslow, UK; 2Department of Chemistry, University of Michigan,…

[ APPLICATION NOTE ] Small Molecule Ion Mobility Investigations into Cross-platform and Long-term Robustness of a CCS Metric Mike McCullagh, 1 Michelle Wood, 2 Nayan Mistry, 2 Severine Goscinny, 3 Petur Dalsgaard4 Waters Corporation, Wilmslow, UK; 2 Sciensano, Brussels, Belgium;…

Application Note Enhanced Identification Confidence and Specificity for PFAS Analysis Using Cyclic Ion Mobility Mass Spectrometry Collision Cross Sections Michael McCullagh, Stuart Adams, Sarah Dowd, Isabel Riba, Hania Khoury-Hollins Waters Corporation For research use only. Not for use in diagnostic…