Does Antithrombin III Block the Action of a Monoclonal Anti-Thrombin Antibody?

Light Scattering for the Masses ® Measuring the Interaction Between Thrombin-α and an Anti-Thrombin Antibody Summary Antibody-antigen binding, hormone-receptor interactions, and many other common biomolecular interactions occur at stoichiometries other than 1:1. The Wyatt Calypso system utilizes composition-gradient multi-angle light…

Light Scattering for the Masses ® Determining the Kinetics of Covalent Thrombin-Antithrombin Association Summary Antithrombin III forms a covalent bond with the catalytic serine of several proteases involved in the coagulation cascade, and the rate of this reaction can increase…

A P P L I C AT I O N N O T E AN3008: Metacomplex Formation & Binding Affinity of Multivalent Binding Partners Sophia Kenrick, Ph.D. and Dan Some, Ph.D., Wyatt Technology Summary Multivalent binding plays a crucial role…

AN3002: Understanding antibody and viral glycoprotein interactions using CG-MALS Kathryn M. Hastie, Ph.D., and Erica Ollmann Saphire, Ph.D., The Scripps Research Institute Summary Viral glycoproteins are often the only antigen found on the viral surface and, as such, are key…