In-depth Characterization of Stressed Bispecific Antibody and Assessment of Batch Consistency by UHPLC-HRAM MS Based Peptide Mapping

APPLICATION NOTE 72916 A high-resolution accurate mass multi-attribute method for critical quality attribute monitoring and new peak detection Authors Haichuan Liu1, Royston Quintyn2, John Rontree3 Thermo Fisher Scientific 1 San Jose, CA 2 West Palm Beach, FL 3 Hemel Hempstead,…

APPLICATION NOTE 73784 High-throughput peptide mapping of trastuzumab using a tandem LC-MS workflow Authors: Sara Carillo ([email protected]), Silvia Millán Martín, and Jonathan Bones NIBRT – The National Institute for Bioprocessing Research and Training, Dublin, Ireland Keywords: Monoclonal antibody, mass spectrometry,…

Application note | 000463 Biopharma The MAM 2.0 workflow enables seamless transition from research and development to quality control Authors Application benefits Hao Yang, Melissa Sato, Royston 1 1 • A MAM method developed on the Thermo Scientific™ Orbitrap Exploris™…

Poster Reprint ASMS 2026 MP 387 A User-Friendly, Regulatory-Compliant Multi-Attribute Method Workflow for Monitoring Critical Quality Attributes and Enabling Method Transfer Lichen Xiu1, Mike Knierman2, Mahsan Miladi1, ssa Sato1, Robert Barkovich, Julie Horner-Buxton1 1 Agilent Technologies, Santa Clara, California 2…