Evaluation of new high pH stable, superficially-porous particle columns for the reversed-phase separation of oligonucleotides

Efficient Reversed-Phase Separation of Oligonucleotides by Using High pH Stable Superficially Porous Columns Agilent Technologie, Inc. Comparison with other columns Resolution of N and N-1 Oligonucleotides Separation of 23-mer RNA-oligonucleotide (2.1 x 50 mm) 21-mer mAU 14 15 N N-1…

Fast and High-Resolution Reversed-Phase Separation of Synthetic Oligonucleotides High-pH-stable, superficially porous particle columns for LC/UV and LC/MS Application Note Biologics and Biosimilars Authors Introduction Phu Duong, Brian A. Bidlingmeyer, Synthetic DNA- and RNA-based oligonucleotides are among many successful biotherapeutic drugs…

Agilent AdvanceBio Oligonucleotide Columns and Oligonucleotide Standards IMPROVE RELIABILITY. REDUCE COSTS. INCREASE FLEXIBILITY. AGILENT ADVANCEBIO OLIGONUCLEOTIDE COLUMNS AND OLIGONUCLEOTIDE STANDARDS HIGH-RESOLUTION OLIGONUCLEOTIDE SEPARATIONS WITH LONG COLUMN LIFETIME ON HPLC AND UHPLC SYSTEMS Synthetic oligonucleotides are promising therapeutic agents for the…

Oligonucleotide Analysis: Practical Techniques and Method Development Optimization for HPLC Mohit Patel LC Columns and Consumables Technical Support December 19, 2023 1 12/19/2023 DE # DE48216954 What Are Oligonucleotide Therapeutic Types? Oligonucleotides are being increasingly developed as therapeutics against a…