Fast and High-Resolution Reversed-Phase Separation of Synthetic Oligonucleotides

Evaluation of new high pH stable, superficially-porous particle columns for the reversed-phase separation of oligonucleotides HPLC 2015 PSB-BIOAN-07 Brian A. Bidlingmeyer, Xiaoli Wang, Stephen Luke* and Phu T Duong Agilent Technologies, Inc., 2850 Centerville Road, Wilmington, DE 19808, US and…

Oligonucleotide Analysis: Practical Techniques and Method Development Optimization for HPLC Mohit Patel LC Columns and Consumables Technical Support December 19, 2023 1 12/19/2023 DE # DE48216954 What Are Oligonucleotide Therapeutic Types? Oligonucleotides are being increasingly developed as therapeutics against a…

Agilent AdvanceBio Oligonucleotide Columns and Oligonucleotide Standards IMPROVE RELIABILITY. REDUCE COSTS. INCREASE FLEXIBILITY. AGILENT ADVANCEBIO OLIGONUCLEOTIDE COLUMNS AND OLIGONUCLEOTIDE STANDARDS HIGH-RESOLUTION OLIGONUCLEOTIDE SEPARATIONS WITH LONG COLUMN LIFETIME ON HPLC AND UHPLC SYSTEMS Synthetic oligonucleotides are promising therapeutic agents for the…

Efficient Reversed-Phase Separation of Oligonucleotides by Using High pH Stable Superficially Porous Columns Agilent Technologie, Inc. Comparison with other columns Resolution of N and N-1 Oligonucleotides Separation of 23-mer RNA-oligonucleotide (2.1 x 50 mm) 21-mer mAU 14 15 N N-1…