Superficially Porous Columns for Semi-Preparative Purification of Synthetic Oligonucleotides

Application Note Biopharma/Pharma Scalable Purification of a Synthetic Oligonucleotide Using Agilent PL-SAX Columns Authors Andrea Angelo P. Tripodi and Andrew Coffey Agilent Technologies, Inc. Abstract Ion-exchange chromatography (IEX) is an effective method for separating and purifying oligonucleotides based on their…

Connor Flannery1, Jordy Hsiao1 Andrea Angelo P. Tripodi2, Andrew Coffey2 Analysis & Purification of Therapeutic Oligonucleotides: Method development optimization from the analytical scale through semi-prep and preparative purification 1Agilent Technologies, Santa Clara, CA HPLC 2024 POSTER # 275 2Agilent Technologies,…

Poster Reprint HPLC 2024 Poster number 275 Analysis & Purification of Therapeutic Oligonucleotides: Method Development Optimization from the Analytical Scale Through Semi-prep and Preparative Purification Connor Flannery1, Jordy Hsiao1 , Andrea Angelo P. Tripodi2, Andrew Coffey2 1Agilent Technologies, Santa Clara,…

An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations: From Analysis to Purification Melissa Goodlad, PhD Columns and Supplies Applications Engineer April 15, 2025 1 April 15, 2025 An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations DE-006001 Introduction to Ion-Paired Reverse-Phase (IP-RP) Separations…