PEGS: IMPROVING ANALYSIS OF QUALITY INDICATING ATTRIBUTES FOR BETTER LIFECYCLE MANAGEMENT

Application Note Migrating Methods from the ACQUITY™ UPLC™ “Classic” System to the ACQUITY Premier System (FL) Robert E. Birdsall, Kellen DeLaney, Pawel Bigos, Tatyana Friedman Waters Corporation Abstract Identifying improvement opportunities in pharmaceutical product lifecycle management is recommended as a…

Application Note Increasing Chromatographic Performance of Acidic Peptides in RPLC-MS-based Assays with ACQUITY PREMIER featuring MaxPeak HPS Technology Robert E. Birdsall, Jacob Kellet, Samantha Ippoliti, Nilini Ranbaduge, Henry Shion, Ying Qing Yu Waters Corporation Abstract Metal-ion mediated adsorption of analytes…

Improving Chromatographic Separations Of Biopharmaceuticals With MaxPeak High Performance Surfaces (HPS) Technology Analytical Solutions Using MaxPeak High Performance Surfaces (HPS) Technology for Biopharmaceutical Therapeutics Biopharmaceutical therapeutics have consistently been the fastest growing segment within the pharmaceutical space and require advances…

Improving Multi-Attribute Method using LC-MS System with Novel Inert Fluidic Pathway Nilini Ranbaduge, Robert E Birdsall, Ying Qing Yu, Weibin Chen, Waters Corporation, Milford, MA Introduction Results Non-specific adsorption of acidic peptides to metal surfaces is a well-known phenomenon affecting…