CE/MS/MS as an Orthogonal Technique for Sensitive and Easy Quantification of Peptides in Complex Matrixes

Poster Reprint ASMS 2024 Poster number WP 587 Targeted Peptide Quantification with Small Foot-print Capillary LC-MS/MS Xiaoli Dong1; Matthew Morse2; Greg Ward2; Linfeng Wu1; Patrick Batoon1; Maozi Liu1 1Agilent Technologies, Inc., Santa Clara, CA; 2Axcend, Provo, UT Introduction Quantification of…

A GENERIC KIT-BASED APPROACH FOR LC-MS/MS QUANTIFICATION OF URINARY ALBUMIN FOR CLINICAL RESEARCH Mary E. Lame, Caitlin M. Dunning, and Erin E. Chambers Waters Corporation 34 Maple Street Milford, MA 01757 DISCUSSION INTRODUCTION [M+2H]2+ VFDEFKPLVEEPQNLIK [M+3H]3+ AEFAEVSK [M+2H]2+ LCTVATLR [M+2H]2+…

[ APPLICATION NOTE ] A Generic Kit-Based Approach for LC-MS/MS Quantification of Urinary Albumin for Clinical Research Mary Lame, Caitlin Dunning, and Erin Chambers Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION High analytical sensitivity LC-MS Albumin (~ MWT 66.5…

The Agilent 6495 Triple Quadrupole LC/MS: Peptide Quantitation Performance Technical Overview Introduction Sample complexity and the low concentration of certain biomarkers are the major challenges encountered when performing biomarker verification using multiple reaction monitoring (MRM)-based methods. For this reason, the…