Enhanced biopharmaceutical characterization using the SELECT SERIES™ MRT

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…

REDEFINED PERFORMANCE ALL THE BENEFITS OF TIME-OF-FLIGHT TECHNOLOGY UNCOMPROMISED CONFIDENCE 2 ULTIMATE RESOLUTION AND MASS ACCURACY AT THE SPEED OF TOF The SELECT™ SERIES MRT delivers the extreme confidence associated with parts per billion mass accuracy, equally at home with…

APPLICATION NOTE 73885 Complete characterization of monoclonal antibodies under native and denaturing conditions Kristina Srzentić1, Eugen Damoc2, Kai Scheffler3, Tom Buchanan4, Krisztina Radi4, Jennifer Sutton1 Thermo Fisher Scientific, 1 Cambridge, Massachusetts, US 2 Bremen, Germany 3 Germering, Germany 4 Hemel…

MEETING DEMANDS FOR IMPROVED MS PERFORMANCE TO SUPPORT DEEPER PRODUCT LC-MS CHARACTERIZATION WITH MULTI-REFLECTING TOF MS TECHNOLOGY Jonathan Fox1, Scott Berger2, Nick Pittman1, Ying Qing Yu2 1Waters Corporation, Wilmslow, Cheshire, UK, 2Waters Corporation, 34 Maple Street, Milford MA, USA. INTRODUCTION…