Optimized Workflow for API Process Impurities using 2D LC-MS/MS

Optimized Workflow for API Process Impurities using 2D LC-MS/MS Claude Mallet,1 Yong Liu,2 and Tim Novack2 1 Waters Corporation, Milford, MA, USA 2 Merck, Rahway, NJ, USA A P P L I C AT I O N B E N…

[ APPLICATION NOTE ] Analysis of Microcystins RR, LY, and YR in Bottled, Tap, and Surface Water Using ACQUITY UPLC Systems with 2D-LC Technology Claude Mallet Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION ■■ Fast extraction protocol (15 min)…

[ APPLICATION NOTEBOOK ] IMPURITIES Developing Safe and Effective Drugs INT RODUCTION NAVIGATION T he pharmaceutical industry is integral in maintaining public health by providing therapeutic and preventative medicines. T he cornerstones of bringing new medicines to market are quality,…

[ APPLICATION NOTE ] Analysis of Microcystins in Urine with 2D-LC-MS/MS – Part III Beatriz Renner M.S.,1 Sabra Botch-Jones M.S.,1 and Claude R. Mallet Ph.D. 2 Boston University School of Medicine, MA, USA 2 Waters Corporation, Milford, MA, USA 1…