Confident intact mass analysis of the tRNA isodecoders of phenylalanine by UHPLC-HRAM-MS and BioPharma Finder software

Comprehensive Characterization of tRNA by Intact Mass Analysis Robert L Ross1, Ryan Cowley2, Keeley Murphy3, Roberto Gamez4, Min Du3 1Thermo Fisher Scientific, Franklin, MA., 2Thermo Fisher Scientific, Sunnyvale, CA., 3Thermo Fisher Scientific Lexington, MA., 4Thermo Fisher Scientific Austin, TX INTRODUCTION…

Application note | 001183 Biopharma Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Authors Application benefits Robert L. Ross1, Jenny England2, Rhonda • Confident identification and sequence confirmation of polyadenylated tails in synthetic…

Scale up your biopharma experiments Orbitrap Ascend BioPharma Tribrid mass spectrometer Scale up biopharma insight Set new standards in biotherapeutic characterization Built to meet the demands of biopharmaceutical experiments, the Thermo Scientific™ Orbitrap™ Ascend BioPharma Tribrid™ mass spectrometer adds innovations…

Application note | 004530 Oligo analysis Comprehensive analysis of nucleic acids across a wide size range using a monodisperse reversed-phase particle platform Authors Application benefits Ke Ma1, Robert Ross2, Min Du2, Shane Bechler1 • High-resolution separation of small oligonucleotides up…