Characterization of mRNA vaccine 5’ and 3’ end products using BioPharma Finder 5.0

Biopharmaceuticals Analytical solutions for mRNA vaccines and therapeutics Table of contents mRNA vaccines and therapeutics mRNA characterization Lipid nanoparticle characterization Critical quality attributes of mRNA therapeutics Direct mRNA sequence confirmation LNP composition analysis by LC-CAD Optimize impurity analysis with ease…

Application note | 001108 Biopharma Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Authors Goal Robert L Ross, Keeley Murphy, Yi Zhang, To develop a sensitive and robust LC-HRAM-MS/MS method…

Application note | 001183 Biopharma Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Authors Application benefits Robert L. Ross1, Jenny England2, Rhonda • Confident identification and sequence confirmation of polyadenylated tails in synthetic…

Application Note LC-MS Analysis of Two mRNA Critical Quality Attributes: 5’-Capping Efficiency and Average Poly(A) Tail Length and Heterogeneity Using the Xevo™ MRT Mass Spectrometer Catalin Doneanua, Alexandre F. Gomesa, Jo-Anne Rileyb, Ying Qing Yua a Waters Corporation, United States…