The impact of Matrix effect in extraction efficiency of N-nitroso-N-methyl-4- aminobutyric acid in Metformin Extended- Release tablets using ESI-LC/HRMS

Application Note Pharmaceutical Small Molecules Simultaneous Determination of Eight Nitrosamine Impurities in Metformin Extended-Release Tablets Using the Agilent 6470 Triple Quadrupole LC/MS Detection of regulated genotoxic impurities from the drug manufacturing process Authors Chander Mani, Kartheek Srinivas Chidella, Saikat Banerjee,…

Application Note Pharmaceutical Small Molecules Simultaneous Determination of Eight Nitrosamine Impurities in Metformin Using the Agilent 6470 Triple Quadrupole LC/MS Detection of regulated genotoxic impurities from the drug manufacturing process Authors Kartheek Srinivas Chidella, Chander Mani, Saikat Banerjee, and Dr.…

Poster Reprint ASMS 2020 WP 555 Determination of Nitrosamine impurities in Losartan Potassium drug substance using Triple Quadrupole Liquid Chromatography Mass Spectrometry Chander Mani ,Saikat Banerjee and Samir Vyas (Agilent Technologies, India.) Introduction The announcement for the recall of ARB…

APPLICATION NOTE 73991 LC-MS/MS method for the quantification of 10 nitrosamine impurities in metformin Authors: Varun Khali, Manoj Kushwaha, Dr. Sachin Pandey, Sunil Kumar, Dr. Biswajayee Patra Thermo Fisher Scientific India Private Limited, Mumbai, India Keywords: Nitrosamine, metformin, nitrosamine impurity,…