Determination of Nitrosamine impurities in Losartan Potassium drug substance using Triple Quadrupole Liquid Chromatography Mass Spectrometry

Application Note Pharmaceutical Small Molecules Simultaneous Determination of Eight Nitrosamine Impurities in Metformin Extended-Release Tablets Using the Agilent 6470 Triple Quadrupole LC/MS Detection of regulated genotoxic impurities from the drug manufacturing process Authors Chander Mani, Kartheek Srinivas Chidella, Saikat Banerjee,…

Application Note Pharmaceutical Small Molecules Simultaneous Determination of Eight Nitrosamine Impurities in Metformin Using the Agilent 6470 Triple Quadrupole LC/MS Detection of regulated genotoxic impurities from the drug manufacturing process Authors Kartheek Srinivas Chidella, Chander Mani, Saikat Banerjee, and Dr.…

Poster Reprint ASMS 2021 Poster number FP744 Highly Sensitive LC-MS/MS Method for Simultaneous and Trace Level Quantification of Ten Nitrosamine Impurities in Olmesartan Medoxomil Chidella Kartheek Srinivas1, Saikat Banerjee1, Kannan Balakrishnan1 , Samir Vyas2 1Agilent Technologies India Pvt Ltd, Bangalore,…

Nitrosamine Impurities Application Guide Confidently Detect and Quantify Mutagenic Impurities in APIs and Drug Products Sartan-Based Losartan Valsartan Candesartan Telmisartan Metformin Ranitidine Nitrosamines are formed by chemical reactions that occur during API manufacturing whether from starting materials, intermediates, reactants, reuse…