Rapid Analysis of mRNA 5’-Capping with High-Resolution LC-MS

Application Note Biopharma Rapid Analysis of mRNA 5' Capping with High Resolution LC/MS Author Brian Liau Agilent Technologies, Inc. Introduction Industrial-scale production of mRNA has received growing attention due to the ongoing SARS-CoV-2 pandemic. mRNA vaccines have proven to be…

Application note | 001108 Biopharma Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Authors Goal Robert L Ross, Keeley Murphy, Yi Zhang, To develop a sensitive and robust LC-HRAM-MS/MS method…

Application Note Biopharma/Pharma Determining mRNA Capping with HILIC-MS on a Low-Adsorption Flow Path Limiting interfering interactions with metal using the Agilent 1290 Infinity II Bio LC System Authors Gerd Vanhoenacker, Kris Morreel, Stefanie Jonckheere, Pat Sandra, and Koen Sandra RIC…

Application Note Analysis of mRNA Cap Impurity Profiles and Capping Efficiency Using RapiZyme™ MC1 Ribonuclease Balasubrahmanyam Addepalli, Tatiana Johnston, Catalin Doneanu, Jamuna Vaishnav, Alexandre Gomes, Christian Reidy, Ying Qing Yu, Matthew A. Lauber Waters Corporation, United States Published on June…