Improved molecular detection and acquisition speed using DESI mass spectrometry imaging quadrupole based mass spectrometer

IMPROVED SELECTIVITY AND ACQUISITION SPEED USING DESI QUADRUPOLE BASED MASS SPECTROMETER 1 Emmanuelle Claude, 1Wei Rao, 2Zoltan Takats, 1Emrys Jones 1 Waters Corporation, Wilmslow, UK; 2Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK INTRODUCTION…

NOVEL TARGETED DESI MRM TQ SYSTEM PROVIDING INCREASED SENSITIVITY AND ACQUISITION SPEED FOR MASS SPECTROMETRY IMAGING Emmanuelle Claude1, Steven Pringle1, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK INTRODUCTION Gefitinib was detected with a S/N ~ 2,500 and was at least…

[ TECHNOLOGY BRIEF ] DESI-Mass Spectrometry Imaging Investigation of Discrete and Cassette Drug Dosed Tissues Philippa J Hart,¹ Andreas Danhorn,² Mark Towers,¹ and Emmanuelle Claude¹ ¹Waters Corporation, Wilmslow, UK, ²Imperial College, London, UK Mass spectrometry imaging for the distribution of…

[ APPLICATION NOTEBOOK ] Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape Small Molecules Oligonucleotide Protein/Peptide Therapeutics Software Tools Targeted Imaging LC-MS/MS Solutions to Support Reliable, Sensitive and Efficient Workflows for the Bioanalysis of Drug Modalities Welcome to the Waters…