DESI-Mass Spectrometry Imaging Investigation of Discrete and Cassette Drug Dosed Tissues

IMPROVED SELECTIVITY AND ACQUISITION SPEED USING DESI QUADRUPOLE BASED MASS SPECTROMETER 1 Emmanuelle Claude, 1Wei Rao, 2Zoltan Takats, 1Emrys Jones 1 Waters Corporation, Wilmslow, UK; 2Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK INTRODUCTION…

Improved molecular detection and acquisition speed using DESI mass spectrometry imaging quadrupole based mass spectrometer Emmanuelle Claude1, Wei Rao1, Zoltan Takats2, Emrys Jones1 1 Waters Corporation, Stamford Rd, Wilmslow, SK9 4AX, UK; 2 Department of Metabolism, Digestion and Reproduction, Imperial…

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

NOVEL TARGETED DESI MRM TQ SYSTEM PROVIDING INCREASED SENSITIVITY AND ACQUISITION SPEED FOR MASS SPECTROMETRY IMAGING Emmanuelle Claude1, Steven Pringle1, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK INTRODUCTION Gefitinib was detected with a S/N ~ 2,500 and was at least…